Chromatin.and.Disease

Chromatin and Disease
300 pages | Sep 22 2010 |ISBN:1402054653 | PDF | 5.5 Mb
The packaging of genomic DNA together with core histones, linker histones, and other functional proteins into chromatin play key roles in nuclear processes such as transcription, replication, repair and recombination. Research in the last two decades has unveiled the fact that many diseases involve an aberration of these processes at the chromatin level