Limbal Stem Cell Transplantation for Limbal Dermoid in a Case of Goldenhar Syndrome

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Added on November 20, 2014 by sns88in Books > Academic
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Abstract
Goldenhar Syndrome (known as Oculoauriculovertebral Syndrome (OAVS) or facioauriculovertebral dysplasia) is a rare congenital defect classically involving eye anomalies with or without anomalous development of the ear, nose, lips, soft palate, mandible and vertebra. It is a morphogenetic anomaly associated with the 1st and 2nd branchial arches. We report a case of 9 months old male child presented with ocular abnormalities. On evaluation, he had the classical signs of this syndrome like limbal dermoids, eyelid coloboma, preauricular skin tags and hemi facial microsomia. This patient was first seen in January 2010 and has been followed and treated for the same. The patient underwent a surgery for right eye limbal dermoid at the age of 4 years. The initial presentation with course of the disease and Post-Surgical outcome is described here. The Authors performed dermoid excision with autologous conjunctiva along with limbal stem cells transplantation and achieved a satisfactory surgical outcome.


Keywords

Limbal Dermoid, Limbal Stem Cell Transplantation, Goldenhar Syndrome


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Limbal Stem Cell Transplantation for Limbal Dermoid in a Case of Goldenhar Syndrome