Prototype 1

Prototype (stylized as [PROTOTYPE]) is an action-adventure open world video game developed by Radical Entertainment and published by Activision. The game was released in North America on June 9, 2009, and in southwestern parts of North America as well as Oceania on June 10, and was released in Europe on June 12.
The game is set in New York City, where a virulent plague known as Blacklight is spreading through Manhattan. Those infected are mutated into hideous monsters of varying form, with an uncontrollable rage to kill all uninfected life-forms and the military force known as blackwatch has been formed to keep the infection from spreading. At the center of it is the protagonist, Alex Mercer, an incredibly powerful shapeshifter with no memory of his past. Parallel to the game's storyline is the ability to play the game as a sandbox-style video game giving the player freedom to roam Manhattan.
Many reviewers compared and contrasted it with Infamous, another action-adventure open world game released one month prior to Prototype, by Sucker Punch Productions which features a superpowered protagonist with developing powers in an urban world. However, the gameplay of Prototype is very similar to The Incredible Hulk: Ultimate Destruction, also by Radical Entertainment.