SPRINGER STUDIES ON MENS HEALTH AND FERTILITY 2012 RETAIL EBOOK-kE

TITLE: STUDIES ON MEN'S HEALTH AND FERTILITY

PUBLISHER: SPRINGER LANGUAGE: ENGLISH

LINK: http://is.gd/yuMJQf RELEASE TYPE: RETAIL

FORMAT: PDF RELEASE DATE: 2014.04.14

ISBN: 9781617797767 STORE DATE: 2012

SAVED.MONEY: 179 EURO DISKCOUNT: 02 x 05MB

AUTHOR: AGARWAL, ASHOK, AITKEN, ROBERT JOHN

ALVAREZ, JUAN G (EDS.)



BOOK



Studies on Men's Health and Fertility provides a comprehensive

series of up-to-the-minute reviews addressing the role of

oxidative stress in the aetiology of reproductive pathologies in

the male. This volume represents by far the most detailed

authoritative review of the field that has been produced to

date. The text encompasses the basic science of reactive oxygen

species (ROS) production by mammalian spermatozoa, the way in

which these highly reactive molecules are processed by the germ

line and the physiological significance of this redox activity in

the generation of a functional gamete. The factors responsible

for perturbing the delicate balance between physiological redox

signaling on the one hand and oxidative stress on the other are

also extensively reviewed and some of the first clues concerning

the underlying mechanisms (age, heat, infection, cryostorage

aberrant lipid metabolism), clearly identified. From a clinical

perspective there are chapters setting out the methods we should

be using to diagnose oxidative stress in the male germ line, a

clinical perspective on the aetiology of this condition and

detailed considerations of the most suitable means of

ameliorating such stress from a therapeutic point of view



Studies on Men's Health and Fertility is intended to provide

clinicians and scientists with a snap shot of the current status

of this exciting, rapidly moving field. The book will be of value

to clinicians interested in strategies for the management of

oxidative stress in their infertility patients and scientists

wishing to understand the molecular mechanisms underpinning the

generation of ROS by these cells and its pathophysiological

significance. It was not so long ago that the ability of

spermatozoa to generate ROS was a hotly disputed topic. With the

publication of this book such doubts can finally be laid to rest

There is now no doubt that these cells actively generate ROS

that oxidative stress is a major contributor to defects in male

reproductive health and that the successful clinical management

of this condition depends on developing a deeper understanding of

the underlying molecular mechanisms. In this quest, Studies on

Men's Health and Fertility will be seen as a clear and important

milestone