The Binding Of Isaac Rebirth OP

OP means OPEN PORTABLE , any DLC or update can be easily added to the portable file

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New Features

The ability to save and return to a game session. This could not be done originally due to Flash limitations.
The remake features local two player co-op, but no online multiplayer as to avoid extending the development time any further (it will not be included in an online patch, either). The second player can join in at any time as a shooting Familiar by pressing "Start" on his/her controller, causing Isaac to lose a Heart Container (which will be given to the new player). Subsequent presses of the start button will give more heart containers to the second player, and Isaac will lose them accordingly.
A feature that allows the player to export a picture of their Isaac after the end of the run will be included.
The game has full-screen support and more resolution options.
There is a "hard mode" for more experienced players, giving away a few new rewards that are unattainable in other difficulties.
Rebirth supports all controllers that would normally work in a non-Flash game.
The various pictures shown of the game only display the basic art; new animated effects will eventually be added, such as fog, smoke, lighting, water drips, moving grass, etc.
Soul Hearts will be capped at the end of the health bar in Rebirth.
Soul Hearts going off the screen in the original game was a bug. They were intended to be capped at the end like regular Heart Containers, but Edmund liked the mystery, and the bug was not patched.
It will be possible to have more than 6 Familiars at a time in Rebirth, which was not possible in the original game.
Rewards for completing bosses/floors/runs under certain times will be provided in order to give an incentive for "speed runs". Most of these rewards are item unlocks.
The game now has more modding support than the original game, although Edmund is unsure as to how he can support modders.
The Polaroid trinket is no longer needed to go to The Chest, and has been changed into a passive item.
Edmund wants to balance unfair rooms and "ham-fisted" bosses that depend on the player's items rather than their skill. He said that he originally wanted The Binding of Isaac to be more of a bullet-hell style game, but it lagged Flash too much, resulting in the current Binding of Isaac.
The "Faith" stat is actually in Rebirth, probably increasing the chance of an Angel Room appearing.
The PS4 and PS Vita versions have multiple save slots available.
The controls of a keyboard/controller are now able to be rebound.

New Content

Items

About 150 new Items have been created, increased the total number of items in the game to 300+. 6 new Pick Ups have also been added.
A Mulligan-like item for Spiders is in the game.
Monstro's Lung, an item that gives isaac a hair lip like Monstro's and gives the ability to charge and shoot multiple blood shots like Monstro.
An "Iron Bar" item.
A new item called the "Midas Touch" that causes enemies killed by contact damage to drop Coins.
A new item called "E-Coli" that spawns Poop when an enemy is killed with contact damage.
Wiggle Worm has been turned into a Trinket, and is included in a set of 4-6 Trinkets that change how Isaac's tears move. (Hook and Ring worm)
Familiars have more interesting effects.
Two new items called the Tiny Planet and Champion Belt were teased. According to Edmund, Tiny Planet greatly increases Isaac's range stat, but makes all tears revolve around his body, similar to Attack Flies. The idea is that there will be multiple tears revolving around him, with each tear stopping after a certain amount of time passes (which depends on Isaac's current range stat). Champion Belt Increases attack power, but in return increases the chances of encountering champion enemies.
Tiny Planet is also affected by special tear-changing effects such as Technology.
The synergies between various tear-changing items have been improved, such as homing and Brimstone, which could result in a homing Brimstone laser in Rebirth. An example of a tear-changing item synergy is shown in the gallery below.
Edmund likes The Candle how it is, but he plans to move it into the higher-priced Shop item tier.
Edmund considers Lemon Mishap to be the joke item of the game, so he doesn't want it to be over-buffed. Still, its range and duration have been increased. It will also become a one room charge.
Brimstone's "Brimsnapping" glitch has been fixed.
The Kamikaze! glitch has been fixed, but the item itself will be buffed, probably by reducing self-damage.
Dr. Fetus and Epic Fetus are the same, but will simply be harder to find. Epic Fetus could be unlocked in a harder challenge, too.
An item that causes Bombs to explode in a cardinal cross pattern (similar to the Bomberman franchise) has been added.
The item Max's Head's name has been changed to "Cricket's Head" (one of Edmund's cats). The item's appearance will also be changed accordingly.
Another "Candle" item may possibly be added.
Edmund has stated that Best Friend will no longer kill Isaac upon explosion anymore, likely as a reference to the bugged hits (which can be instant death).
A store-exclusive jar item that can store hearts.
A Black Heart pickup that functions like a Soul Heart, but damages enemies when depleted.
A "Ball of Tar" item that makes Isaac look like Gish and makes him randomly shoot slowing tears.
A Guppy's Collar item that grants an unlimited 50% chance to respawn on death.
A new dice item.
A Mulligan follower.
A follower that looks similar to a Boom Fly.
A headless baby follower that leaves a blood trail.
An item that makes Isaac fart when picking up money.

Characters

4 new playable characters. Eden, Lazarus, Azazel and The Lost.
Eden starts with random, evenly balanced Stats and two random Items. To play as Eden, a token of some sort has to be paid, which can be achieved from defeating Mom (or possibly other final bosses). Edmund says that there will be some balancing mechanic preventing the player from rolling an extremely powerful (or extremely underpowered) character right from the start.
Lazarus is unlocked by having 4+ Soul Hearts in one run. He starts with 1 extra life. If he is defeated in a room he is brought back to life within that room with 1 heart .
The Lost is a secret character unlocked by dying on certain floors by certain enemies as certain characters. This character starts with no hearts and can not pick up hearts. The Lost also starts with flying. Defeating every normal boss as The Lost unlocks the God Head.
has written up an idea for a possible playable character for Rebirth that fans of Loki will like.
Edmund says that he does want to balance the characters, but not in terms of their stats. Certain characters being harder to play is supposed to be a part of the game.
It will be possible to pick different starting item loadouts for different characters, with subtle visual changes.

Enemies & Bosses

25 enemies and 16 bosses have been completed as of 17 October 2013.
Three New bosses have been teased, Dingle, The Haunt (Both shown in the gallery below) and Mega Maw
Three new enemies has been confirmed, the Fatty (shown in the gallery below) the Nest, and Bony. The Fatty are similar to Gapers as it has a chance to turn into another enemy when killed, the Nest is a Spider version of the Hive spawning a Butt Spider upon death, and finally the Bony who are remains of an unknown monster, it has an A.I identical to Knights but instead will stop and throw a bone in Isaac's direction then continuing to walk in whatever direction it was facing.
The Isaac and ??? boss fights will be less similar to each other in Rebirth.
Champion enemies will be more different in new ways.
All Champion enemies now drop specific items based on their suit of color and will have special abilities such as invisibility (Black), leaving a trail of green slime (Green), or attracting tears to themselves (Purple).
A new floating enemy.
Spider-like enemies that crawl along the walls and shoot a barrage of three blood shots.

Rooms & Floors

New special rooms like the Curse Room will be added in Rebirth.
Rooms will come in different shapes and sizes, some being so large that the screen will scroll when Isaac walks around them.
Room configurations with 3, 2 or one possible entrances can appear (e.g. rooms with only a single walkway to the other side).
More environmental hazards like Cobwebs and Spikes will be implemented, but no "slippery" hazards like ice, since Edmund dislikes them.
A new final chapter will be added, along with new endings.
Choosing between Sheol and the Cathedral will be more meaningful by making Sheol more interesting and difficult. Edmund also hinted at another "The Chest"-like level for Sheol.
Shops will be more important in Rebirth, although there will still be only 1 shop per floor. There will be 20 cent items, and various new items will be added to the Item Pool.
Edmund has said that Sacrifice Rooms will be more interesting in Rebirth.
More Curses and graphical reworks for already existing ones will be added.
Spikes that retract into the floor.
Edmund might possibly add an angel counterpart of Krampus for Angel Rooms.

Other

Various new Challenges, such as an "All-Champion Enemies" challenge. No custom runs will added, however.
Edmund wants to add new secrets that can be unlocked by performing certain actions. For example, using the We Need To Go Deeper! item in Sheol does nothing in the original game, but doing this in Rebirth could uncover new secrets.
There will be a lot of changes to the effect of the "Everything's Terrible" secret achievement.
Edmund might "do a bestiary like spelunky did", but he will never add detailed item descriptions.
Brimstone horns hats will be available for Team Fortress 2 to the people who preordered the game on steam.
A new type of Beggar who asks for keys.
Beggars will look at nearby Beggars.
Decorative pots.

* enjoy ...