Understanding the Principles of Organic Chemistry (gnv64)

Understanding the Principles of Organic Chemistry - A Laboratory Experience
By Steven F. Pedersen, Arlyn M. Myers
Brooks Cole | January 2010 | PDF | ISBN 10: 0495829935 | 432 pages | 16 mb
Amazon Link : http://www.amazon.com/Understanding-Principles-Organic-Chemistry-Laboratory/dp/0495829935/

Class-tested by thousands of students and using simple equipment and green chemistry ideas, UNDERSTANDING THE PRINCIPLES OF ORGANIC CHEMISTRY: A LABORATORY COURSE includes 36 experiments that introduce traditional, as well as recently developed synthetic methods. Offering up-to-date and novel experiments not found in other lab manuals, this innovative book focuses on safety, gives students practice in the basic techniques used in the organic lab, and includes microscale experiments, many drawn from the recent literature. An Online Instructor's Manual available on the book's instructor's companion website includes helpful information, including instructors' notes, pre-lab meeting notes, experiment completion times, answers to end-of-experiment questions, video clips of techniques, and more.

TABLE OF CONTENTS
Preface to the Student xi
Preface to the Instructor xiv
The Front Cover: Nature’s Organic Chemistry Laboratory xix

PART I Theory and Techniques
Chapter 1 Safety in the Chemistry Laboratory 3
Chapter 2 The Laboratory Notebook and the Laboratory Period 9
Chapter 3 Where to Find It: Searching the Literature 13
Chapter 4 Things You Need to Know Before You Begin 15
Chapter 5 Properties of Organic Molecules 31
Chapter 6 Characteristic Physical Properties of Pure Compounds 53
Chapter 7 Isolation and Purification of Compounds 89
Chapter 8 Structure Determination 141
Chapter 9 Running a Synthetic Reaction 201

PART II Experiments
Experiment 1 Calibrating a Pasteur Pipette 211
Experiment 2 Investigating Solubility and Acid-Base Reactions 214
Experiment 3 Mixed Melting Points 219
Experiment 4 Whittling Down the Possibilities: Identifying an Unknown Using Molecular
Dipole Moment, Solubility, Density, and Boiling Point Data 224
Experiment 5 Recrystallization and Melting Points: Recrystallization of Adipic
and Salicylic Acids 230
Experiment 6 Recrystallization and Melting Points: Recrystallization of an Unknown
Solid and Decolorization of Brown Sugar 236
Experiment 7 Thin Layer Chromatography (TLC) 241
Experiment 8 Identification of an Adulterated Herb or Spice by Thin Layer
Chromatography (TLC) 246
Experiment 9 What Do You Take for Pain? 253
Experiment 10 Nucleophilic Substitution Reactions of Alkyl Halides 257
Experiment 11 Isolation of Trimyristin from Nutmeg 261
Experiment 12 The MagtrieveTM Oxidation of 4-Chlorobenzyl Alcohol,
A Solvent-Free Reaction 268
Experiment 13 The Sodium Borohydride Reduction of Benzil and Benzoin 273
Experiment 14 The Grignard Reaction: The Preparation of 1,1-Diphenylethanol 278
Experiment 15 The Asymmetric Dihydroxylation of trans-Stilbene 285
Experiment 16 Some Chemistry of a-Pinene Oxide 291
Experiment 17 A Dehydrogenation/Hydrogenation Reaction 296
Experiment 18 The Friedel-Crafts Reaction 303
Experiment 19 Microwave Heating of Organic Compounds 307
Experiment 20 The Reaction of 1,1-Diphenylethanol on Clay in the Presence
of Microwave Radiation 312
Experiment 21 The Wittig Reaction 316
Experiment 22 The Suzuki Reaction 321
Experiment 23 The Crossed-Aldol Condensation 326
Experiment 24 Identifying the Structure of an Aldehyde by Qualitative Analysis 331
Experiment 25 The Benzoin Reaction 338
Experiment 26 The Diels-Alder Reaction 344
Experiment 27 Synthesis of an a,b-Unsaturated Carboxylic Acid Derivative 348
Experiment 28 The Reaction of 2-Acetylphenyl Benzoate with Potassium Hydroxide.
Part I 355
Experiment 29 The Reaction of 2-Acetylphenyl Benzoate with Potassium Hydroxide.
Part II 359
Experiment 30 Synthesis of 1,2,3,4-Tetrahydro-b-Carboline 363
Experiment 31 Base-Catalyzed Hydrolysis of Nicotinonitrile Using an Anion-Exchange
Resin 367
Experiment 32 Reactions of Salicylamide 371
Experiment 33 The Hunsdiecker Reaction 377
Experiment 34 The Investigation of the Mechanism of a Reaction 381
Experiment 35 Monoterpenes and the Ritter Reaction 385
Experiment 36 Chemoselectivity in Transfer-Hydrogenation Reactions 389